New PhD studentships for October 2021 start

We are starting to recruit PhD researchers for Oct 2021 start. Join a world-class, interdisciplinary and highly supportive research environment where you can learn about new cell biology projects and advanced microscopy techniques. Below, are the projects that are currently open to application. "Developing an ultra-fast and unbiased histopathology toolkit" We will develop a novel protocol …

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Preprint outlining the utility of peptide ligands against RyR2 as potential super-resolution imaging probes

Our latest pre-print is now online, where we evaluated two peptide ligands of the cardiac ryanodine receptor (RyR) as super-resolution imaging probes. The research was conducted in collaboration with one of our industrial partners, Badrilla Ltd., during the industrial internship of iCASE PhD student Tom Sheard funded through the DiMeN DTP. The peptides used were the scorpion …

New book chapter detailing EExM in Methods in Cell Biology

Our new book chapter has been published, detailing the enhanced expansion microscopy technique (EExM). The protocol offers a route to visualising cellular ultrastructures at a resolution of 15 nm in-plane (and ~ 35 nm axially) with a hydrogel-based molecular-scale imprint of the fluorescence pattern. We detail how we used EExM to explore structural and biochemical …

Optical microscopy bottlenecks survey

We have launched a brief survey examining the needs in the Life Sciences around the use or potential utility of optical (fluorescence) microscopies. This takes ~ 6 minutes to complete and gives you an opportunity to stay in touch or engaged directly with the new developments of the newly launched UKRI Future Leader Fellowship within …

We have arrived in Sheffield

1st of May - We have officially moved our research operations to the Department of Molecular Biology & Biotechnology in our new home institute, the University of Sheffield. We will be based in the famous Firth Court, working closely with a wide range of interdisciplinary research groups and the IMAGINE imaging consortium.  The UK is …